The Biohacking Beauty Podcast
Biohacking Beauty Podcast
the NAD+ thief your skin can't escape: CD38, zombie cells, and the decline
Most people know NAD+ as a supplement trend. But very few understand what's actually happening inside their skin cells when it runs out or what's stealing it in the first place. By the time you're 45, you've lost half of the molecule that powers virtually every function keeping your skin young. Sadly, it only gets worse from there. The enzyme your skin uses for DNA repair can wipe out up to 90% of what's left after a single afternoon in the sun. This isn't a slow, graceful decline. It's a collapse happening beneath the surface long before the wrinkles appear. In this episode, we will nerd out and break down exactly why NAD+ disappears, who the thieves are, and what the science actually says about getting it back. From the sirtuin-PARP-CD38 trifecta to the zombie cell feedback loop that accelerates the drain with age, this is the most complete picture of NAD+ and skin aging we've put together to date. We also cover the real differences between NMN, NR, and niacin, why the precursor you choose actually matters, and what to stack with it to protect your methylation pathways.Ready to nerd out in this with us? Let's dive in!
the NAD+ thief your skin can't escape: CD38, zombie cells, and the decline
Most people know NAD+ as a supplement trend. But very few understand what's actually happening inside their skin cells when it runs out or what's stealing it in the first...
Dani Conway: the gut-liver detox connection & how gut issues show up as skin issues
Most people treat their skin like a surface problem. But almost every persistent skin issue, from rosacea to eczema to accelerated aging, has something deeper driving it. That deeper driver is almost always the gut, the liver, or a backed-up detox pathway. We at Young Goose, always believe that skincare is whole body care and we want our community to identify the deeper causes of skin issues that products alone can’t fix. In this episode, functional nutrition practitioner Dani Conway joins us to break down why the skin is not the origin of the problem but the exit sign. When the body cannot eliminate toxins efficiently, they take the path of least resistance. For a lot of women, that path is the skin on their faces. Dani brings nearly 20 years of clinical practice to this conversation, along with a sharp, evidence-grounded perspective on why fixing hormones first is often the wrong starting point and what to address instead. We go deeper into this in the latest episode of Biohacking Beauty: The Anti-Aging Skincare Podcast. We also cover how to deal with food sensitivities, common misconceptions around hormones and blood sugar testing, and the use of GLP-1 and peptide use.
Dani Conway: the gut-liver detox connection & how gut issues show up as skin issues
Most people treat their skin like a surface problem. But almost every persistent skin issue, from rosacea to eczema to accelerated aging, has something deeper driving it. That deeper driver...
skin barrier protocol: how one reset makes every other skincare step work
Most people think that the stinging feeling, redness or tightness are always good signs of skin detoxification. Tricky enough, it can look like ‘glass skin’ or skin renewal. However, almost always the temporary tight and bright skin is a skin barrier issue in disguise. Skin barrier damage is one of the most misread signals in skincare. It looks like purging but it is actually your skin telling you it has been pushed past its limit. It’s easy to think there’s no damage at all because overexfoliation can temporarily give a satisfying baby skin at the cost of long-term skin wellness. One of the best ways to distinguish normal skin stimulation versus barrier damage is to understand your skin biology. As Anastasia always says, "We're not chasing a 10-day glow. We're chasing a 10-year outcome." We go deeper into this in the latest episode of Biohacking Beauty: The Anti-Aging Skincare Podcast. We also cover what real skin barrier repair should feel like, the pillars of skin wellness, and how to listen better to your skin to train it to become more resilient.
skin barrier protocol: how one reset makes every other skincare step work
Most people think that the stinging feeling, redness or tightness are always good signs of skin detoxification. Tricky enough, it can look like ‘glass skin’ or skin renewal. However, almost...
sleep is skincare: how timing unlocks your body's best skin repair
Did you know that the most powerful anti-aging protocol isn't about how long you sleep? It's about when. Getting eight hours of sleep for skincare feels like a tough feat to achieve especially when life gets in the way. By understanding how your skin begins its optimal repair time, it’s still possible to achieve the best skin results without the guilt of not sleeping enough. In our quest in finding the best skincare ingredient for our products, we discovered that hours of sleep do matter, but best skin results happen by following the skin’s optimal program sequences for deep repair. We go deeper into this in the latest episode of Biohacking Beauty: The Anti-Aging Skincare Podcast. We also cover how melatonin onset, circadian rhythm, growth hormones, and inflammation play a huge role in giving your skin the environment it needs to do its best work.
sleep is skincare: how timing unlocks your body's best skin repair
Did you know that the most powerful anti-aging protocol isn't about how long you sleep? It's about when. Getting eight hours of sleep for skincare feels like a tough feat...
Alex Tarnava: what hydrogen really does to your skin
Molecular hydrogen is often described as a selective antioxidant, but that framing is incomplete. In this episode, we explore hydrogen as a mitochondrial hormetic signal that can influence redox balance, inflammatory regulation, and adaptive stress pathways. The key distinction is that delivery route changes mechanism. Oral, inhaled, and topical hydrogen act differently in the body, with different kinetics, tissue distribution, and biological implications. We dive deeper into this in the Biohacking Beauty Podcast with Alex Tarnava. We discuss why topical hydrogen is gaining attention for skin outcomes, how gut-mediated signaling may drive systemic effects, and why interpreting evidence requires understanding study design, delivery method, and real-world product variability.
Alex Tarnava: what hydrogen really does to your skin
Molecular hydrogen is often described as a selective antioxidant, but that framing is incomplete. In this episode, we explore hydrogen as a mitochondrial hormetic signal that can influence redox balance,...
Dr. Scott Sherr: why chronic stress disrupts mitochondria and accelerates visible skin aging
Chronic stress isn’t just a mental or emotional burden. It creates a biological cascade that disrupts mitochondrial function, accelerates inflammation, and shows up visibly in the skin long before deeper symptoms appear. We dive deeper into this in the Biohacking Beauty Podcast with Dr. Scott Sherr. We also talk about the sympathetic spiral of doom, why skin reflects mitochondrial decline before other symptoms appear, and why sequencing interventions matter more than intensity. Dr. Scott Sherr is a board-certified internal medicine physician certified in Health Optimization Medicine (HOMe) and a specialist in Hyperbaric Oxygen Therapy. He is the COO of Troscriptions and focuses clinically on mitochondrial health, stress physiology, and advanced recovery protocols.
Dr. Scott Sherr: why chronic stress disrupts mitochondria and accelerates visible skin aging
Chronic stress isn’t just a mental or emotional burden. It creates a biological cascade that disrupts mitochondrial function, accelerates inflammation, and shows up visibly in the skin long before deeper...