Biohacking Beauty Podcast

collagen vs. elastin for skin aging: why collagen is over-credited

collagen vs. elastin for skin aging: why collagen is over-credited

Skin sagging, crepiness, and loss of bounce are often blamed on collagen loss, yet the real driver sits elsewhere in the skin’s architecture. Elastin degradation accumulates quietly over time, shaping how skin functions long before changes fully register in the mirror. In this Biohacking Beauty episode, we unpack why rebuilding elastin is largely a myth, how elastin breakdown differs fundamentally from collagen loss, and how even a single period of stress can influence skin integrity for decades. We also examine how collagen is over-credited in conversations about sagging and how lasers and radiofrequency treatments can create temporary tightening while promoting long-term fibrotic remodeling that undermines true elasticity. Tune in.

collagen vs. elastin for skin aging: why collagen is over-credited

Skin sagging, crepiness, and loss of bounce are often blamed on collagen loss, yet the real driver sits elsewhere in the skin’s architecture. Elastin degradation accumulates quietly over time, shaping...

Dylan Gemelli: injectable peptides, PRP exosomes and skin repair outcomes

Dylan Gemelli: injectable peptides, PRP exosomes and skin repair outcomes

Most conversations about advanced skin treatments stay at the surface, particularly around regenerative approaches, overlooking why lasting results are so hard to achieve. We dive deeper into this in the latest Biohacking Beauty episode with Dylan Gemelli. We explore why oral peptides often fall short, and how BPC-157 relates to gut healing, inflammation resolution, and collagen repair. We also unpack the real mechanism behind PRP facials, and how neuromodulating peptides compare to Botox over the long term. Dylan Gemelli is a prominent figure in the fitness and biohacking space and the host of the Dylan Gemelli Podcast. He is currently completing a master’s degree in dietetics and holds certifications as an integrative health professional and cellular health advisor, with his work centered on educating audiences about peptides, longevity, cellular health, nutrition, and neuroscience.

Dylan Gemelli: injectable peptides, PRP exosomes and skin repair outcomes

Most conversations about advanced skin treatments stay at the surface, particularly around regenerative approaches, overlooking why lasting results are so hard to achieve. We dive deeper into this in the...

how winter accelerates skin aging and the best protocols to reverse It

how winter accelerates skin aging and the best protocols to reverse It

Ever wonder why your skin changes so much in winter?  In this episode of Biohacking Beauty, we explain what actually happens when humidity drops, TEWL rises and indoor heating pulls moisture from the skin. We also talk about UVA exposure in cold months, lifestyle shifts that increase oxidative stress and why winter puts more pressure on your skin’s repair systems. We break down the winter ingredients that matter most, like ceramides, barrier lipids, vitamin F, beta glucan, hyaluronic acid, peptides, NAD precursors and exosomes, and how to use them in a routine that supports barrier strength and cellular energy. We also share simple protocol adjustments for different climates and biological skin ages. If you want a clear strategy for keeping your skin healthy and supported through the colder months, this episode gives you everything you need.

how winter accelerates skin aging and the best protocols to reverse It

Ever wonder why your skin changes so much in winter?  In this episode of Biohacking Beauty, we explain what actually happens when humidity drops, TEWL rises and indoor heating pulls...

Dr. Sarah Daccarett: Hormones, Stress & Why Women Age Faster Than Men

Dr. Sarah Daccarett: Hormones, Stress & Why Women Age Faster Than Men

What if stress isn’t the reason your hormones are crashing, what if it’s the other way around? In this episode of Biohacking Beauty, we sit down with longevity clinician Dr. Sarah Daccarett to explore how early hormone decline sets women up for stress intolerance, immune dysfunction, and accelerated aging. We will explain why telling women to “just de-stress” misses the point, how estrogen and progesterone regulate immune balance, and why autoimmune disease skyrockets when these hormones drop. We also dive into the role of environmental toxins and birth control in shutting down protective signaling, and why most standard hormone therapies fail because of outdated formulations and delivery systems. You’ll hear why optimizing hormones in your 20s and 30s is critical for skin health, sleep, and vitality, why waiting until menopause is too late, and how Sarah is rethinking women’s health. Dr. Sarah Daccarett is the founder of InnerBalance, a telehealth platform rethinking women’s hormone optimization with clinically precise dosing, advanced delivery systems, and ongoing clinical support in 46 states.

Dr. Sarah Daccarett: Hormones, Stress & Why Women Age Faster Than Men

What if stress isn’t the reason your hormones are crashing, what if it’s the other way around? In this episode of Biohacking Beauty, we sit down with longevity clinician Dr....

Why We Had to Reinvent the Facial Mist (And Why This One Works)

Why We Had to Reinvent the Facial Mist (And Why This One Works)

Why do most facial sprays feel great, but deliver nothing long term? In this episode of Biohacking Beauty, we reveal the science behind our new Blue Peptide Spray, the first mist with a clinical dose of methylene blue, plus NAD+ precursors, GHK-Cu, and SOD. It’s designed to optimize mitochondrial energy, reduce oxidative stress, and support true skin repair. We break down why methylene blue acts as a cyclic antioxidant, how it stacks with other longevity ingredients for visible results, and how our anti-staining technology makes it safe for daily use, even over makeup. You’ll learn why this spray doesn’t just hydrate, it upgrades everything that comes after it. From improved collagen signaling to enhanced barrier recovery, Blue Peptide Spray sets a new standard in functional skincare.

Why We Had to Reinvent the Facial Mist (And Why This One Works)

Why do most facial sprays feel great, but deliver nothing long term? In this episode of Biohacking Beauty, we reveal the science behind our new Blue Peptide Spray, the first...

Why Collagen Doesn’t Work Without Vitamin C + Other Supplement Truths

Why Collagen Doesn’t Work Without Vitamin C + Other Supplement Truths

What if your collagen cream isn’t working, because your skin doesn’t have the raw materials to use it?In this episode of Biohacking Beauty we reveal the missing half of most people’s skincare: the internal protocol. From vitamin C as a collagen cofactor (“10x harder for your skin to build collagen without it”) to the role of omega-3s in plumping skin from the inside out, this episode lays out a step-by-step supplement strategy for real skin longevity. We break down why oral hyaluronic acid outperforms topical forms in clinical trials, why senescent cells are not the root cause of aging (just a symptom), and how bioactives like NMN, ergothioneine, and astaxanthin actually get expressed in the skin, unlike most topicals. We also discuss trends like matcha and how it outperforms coffee for skin health, and why oral senolytics like fisetin help eliminate zombie cells that drive inflammation and visible aging. You don't want to miss this one! 

Why Collagen Doesn’t Work Without Vitamin C + Other Supplement Truths

What if your collagen cream isn’t working, because your skin doesn’t have the raw materials to use it?In this episode of Biohacking Beauty we reveal the missing half of most...