NAD+ APEX™

most topical NMN never gets where it needs to go

NMN is one of the most promising NAD+ precursors in skin longevity. But there is a problem the category does not talk about: NMN is water-soluble, and your skin barrier is built from lipids. That mismatch means most topical NMN sits on the surface, where it can do little for the living layers of skin underneath.

NAD+ APEX™ was built to solve exactly this. It pairs encapsulated NMN, engineered to cross the skin barrier, with a recycling booster designed to support the skin's own NAD+ pathway. The difference is not the ingredient. It is the delivery.

6.2×

higher permeability

~20×

more efficient per unit of active

800µm

into the papillary dermis

HOW IT COMPARES

standard topical NMN vs. NAD+ APEX™

Standard topical NMN

Standard topical NMN

Young Goose NAD+ APEX™

Young Goose NAD+ APEX™

Gets through the barrier
Largely sits on the surface
6.2x higher permeability
Delivery per active NMN
Raw isolate in a standard vehicle
~20x more efficient per unit of active
Reaches the living layers
~150-200 µm (superficial)
~800 µm, into the papillary dermis
Supports NAD+ recycling
Ingredient only
Encapsulated NMN + recycling booster
Standard topical NMN

Standard topical NMN

Young Goose NAD+ APEX™

Young Goose NAD+ APEX™

Gets through the barrier

Largely sits on the surface

6.2x higher permeability

Delivery per active NMN

Raw isolate in a standard vehicle

~20x more efficient per unit of active

Reaches the living layers

~150-200 µm (superficial)

~800 µm, into the papillary dermis

Supports NAD+ recycling

Ingredient only

Encapsulated NMN + recycling booster

In plain questions

does topical NMN actually absorb?

On its own, not well. NMN is water-soluble and the skin barrier is lipid-rich, so most formulas leave the active stranded on the surface.

In PAMPA-Skin permeability testing, NMN delivered through our encapsulated system crossed a model of the skin barrier approximately 6.2 times more readily than standard NMN isolate. Proven to deliver NMN 6.2x more effectively into the skin than standard formulations.

The point is delivery: NMN that reaches the living layers of the skin, where it can support the skin's NAD+ pathway.

is more NMN actually better?

This is where the category gets it backwards. A standard isolate can be ~97% NMN and still deliver almost nothing, because concentration is not the same as delivery.

The encapsulated delivery material in our testing contained roughly 5% NMN. When you evaluate the permeability result relative to active NMN content, the encapsulated formulation showed approximately 20x greater delivery efficiency per unit of active NMN than conventional isolate in a standard vehicle.

A small amount, delivered, outperforms a large amount that never crosses the barrier.

Depth of penetration chart

how deep does it actually reach?

Separate Raman imaging studies measured how far the lipid-micellar delivery platform traveled within the skin compared to conventional emulsions.

The studies observed penetration depths of approximately 800 µm, reaching the papillary dermis, whereas standard emulsions stayed largely within the superficial epidermis (~150-200 µm).

This suggests improved transport and retention of the active where skin cells can actually use it.

how does the delivery system work?

The encapsulated component uses DermaSNEDS™, a lipid-micellar delivery platform built to make NMN compatible with the skin barrier. Lipid microdomains of lecithin, phytosterols, and stabilizing lipids interact with the skin’s own intercellular lipids — carrying NMN through the barrier and releasing it gradually within the viable epidermis.

01

encapsulate

A lipid micelle wraps the water-soluble NMN so it can travel through a lipid barrier.

02

fuse

Micelles merge with the skin’s own intercellular lipids, crossing the barrier.

03

release

NMN is released gradually in the viable epidermis — localized NAD+ support where cells use it.

50%

the drop in skin NAD+ between ages 20 and 60

A formula that cannot deliver its NAD+ precursor past the surface is solving the wrong problem.

NAD+ APEX™ is our answer: get the precursor into the living layers, and support the skin's ability to recycle its own NAD+. That is the difference between a trending ingredient and a longevity system.

NAD+ APEX™ powers our YouTH line of products

  • YOUTH RESET

    YOUTH RESET

    YOUTH RESET

    Anti-Aging Serum
    $196.50 USD
    $196.50 USD
  • YOUTH DAILY

    YOUTH DAILY

    YOUTH DAILY

    Skin Longevity Moisturizer
    $176.50 USD
    $176.50 USD
  • YOUTH FIRMING BODY CREAM

    YOUTH FIRMING BODY CREAM

    YOUTH FIRMING BODY CREAM

    NAD+ Powered Body Renewal
    $125.00 USD
    $125.00 USD
  • YOUTH FIRMING NECK & CHEST

    YOUTH FIRMING NECK & CHEST

    YOUTH FIRMING NECK & CHEST

    Focused Neck & Décolleté Restoration
    $200.00 USD
    $200.00 USD

testing and methodology

Permeability testing used a PAMPA-Skin model designed to simulate passive diffusion across a lipidic skin barrier. Raman imaging studies evaluating penetration depth and intradermal deposition were performed at the Jagiellonian Center for Innovation (JCI), Kraków, Poland.